Treatment options

Which form of TRT fits your life?

There is no single best form of testosterone.

Injections, gels and tablets all deliver the same hormone. What differs is how often you take it, how steady your levels stay, and how it fits your week.

Illustration of a man in a teal t-shirt tipping his head back to swallow a capsule.

What matters to you

Compare the four ways testosterone is given

Pick what matters most and we'll show which option tends to fit. More than one may light up, but you only ever take one form of treatment, chosen with your doctor. It's a starting point for that conversation, not a prescription.

Pick one or more and we'll highlight the closest fit.

Weekly self-injection

Arc's usual route

Short-acting testosterone you inject yourself at home, once or twice a week.

How it's taken
A small injection you give yourself at home, under the skin or into muscle. We teach you.
How often
Once or twice a week
Steady levels
Steadiness of levels: 4 out of 4
Convenience
Convenience: 3 out of 4
Needle-free
Uses a needle
Transfer risk
None
Time to feel it
3 to 6 weeks
Typical costrelative, 1 dot is lowest
Relative cost: 1 out of 4
Tends to suit
Men who want the steadiest levels and precise dose changes, and don't mind a quick weekly routine.

Cost is relative medication and administration cost in general terms, not Arc's prices. See pricing. Which option you are offered, if any, is a decision for you and your prescribing doctor.

Behind the injection column

Why the ester matters

Injectable testosterone is attached to an ester, a molecule that controls how quickly the hormone is released once injected. The ester changes the timing, not the testosterone. Enantate, cypionate and Sustanon release over days, which is why they suit a weekly or twice-weekly routine with steady levels. Undecanoate releases over months, which is why the long-acting injection is given every 10 to 14 weeks and why levels peak after each dose and dip before the next.

In the UK, enantate, Sustanon and undecanoate are licensed medicines. Cypionate is not, and is supplied as an unlicensed import on a prescriber's order. Which you receive, if any, is your prescriber's decision.

Alongside TRT

Not forms of TRT, but part of the same conversation

Two medicines come up in almost every consultation about treatment options. Neither replaces testosterone in the comparison above, and both are a prescriber's call.
  • hCG

    Human chorionic gonadotropin mimics luteinising hormone, so the testes keep working while you are on testosterone. It is used where fertility or testicular volume matters. It helps but does not guarantee fertility.

  • Enclomiphene

    Raises your own testosterone rather than replacing it, so it is an alternative to TRT for some men, not a form of it. It is unlicensed in the UK and only ever a prescriber's decision.

How we choose with you

The method follows your response, not the other way round

The comparison above narrows the field. The decision is made in a consultation, and revisited as your bloods come back.
  1. 01

    Talk it through

    Your doctor reviews your bloods, symptoms, medical history, fertility plans and the shape of your week, then talks through the options that realistically fit.
  2. 02

    Start, with training

    If injections suit you, we teach you to self-inject before you do it alone. Gel and tablet users get the same walkthrough on technique, timing and precautions.
  3. 03

    Check and adjust

    Repeat bloods a few weeks in show how you respond. Doses change, and occasionally the method does, based on your numbers and how you feel.
  4. 04

    Keep monitoring

    Testosterone, oestradiol, haematocrit and PSA on a schedule for as long as you are on treatment. Whatever the method, the monitoring is the same.

FAQs

Your TRT questions, answered.

Which form of TRT is best?

There isn't one. Injections, gels and tablets all deliver the same hormone. What differs is how often you take it, how steady your levels stay and how it fits your routine. Weekly or twice-weekly injections give the flattest levels and the most precise dose changes, which is why they are our usual starting point, but a man who will not inject is better served by a gel he actually uses.

Do I have to inject myself?

No. Gels, creams and tablets are needle-free, and the long-acting injection is given by a nurse rather than by you. If you do choose injections, we teach you to do it yourself at home. Most men find the first one is the hardest and the rest become routine.

How often are testosterone injections?

With the short-acting esters we usually prescribe, once or twice a week. Smaller, more frequent doses keep levels steadier than one large dose. The long-acting undecanoate injection is given every 10 to 14 weeks, usually at a clinic or GP surgery. There is more on technique and timing in our guide to where to inject testosterone.

Can I get the long-acting injection privately, or only on the NHS?

It is the standard NHS option, and private clinics can prescribe it too. We rarely use it as a first choice because of the peak after each dose and the dip in the weeks before the next, which some men feel as a return of their symptoms. If you are stable on it and feel well, there is no reason to change.

Does the method change the side effects or the monitoring?

The monitoring is the same whichever form you use: testosterone, oestradiol, haematocrit and PSA on a schedule, because the risks come from the hormone rather than the delivery. A few things are method-specific: injection-site discomfort, skin irritation and transfer risk with gels, and the need to take tablets with food.

Do gels or tablets affect fertility less than injections?

No. Any external testosterone suppresses the signal from the brain to the testes, so sperm production falls whichever way it is delivered. If fertility matters to you, that is a conversation about hCG alongside treatment, or enclomiphene instead of it, before you start.

Can I switch from one form to another?

Yes. Men move from gel to injections when absorption is poor or the daily routine slips, and from injections to gel when they want to stop using needles. A switch needs a dose recalculation and a blood test a few weeks later, so it is done with your doctor rather than on your own.

Which form of TRT is easiest to travel with?

Tablets and the long-acting injection are the simplest, since there are no needles to carry or, with the long-acting injection, nothing to take with you on most trips. Weekly injections and gel travel fine too: keep them in your hand luggage with a travel letter from us, and check your airline's rules on needles. More on travelling with TRT.

Can I choose which product I'm prescribed?

You can and should discuss it. The decision sits with your prescribing doctor, who has to justify the choice clinically, and UK law stops clinics advertising specific prescription-only medicines to the public. We will tell you what we are prescribing and why, in your consultation.

Testosterone matters.
Let's treat it properly.

Medical care that puts you back in control, with proper testing, expert oversight and treatment tailored to you.

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